Australian Scientists develop a new diagnostic technique, using gold-plated nanoparticles, to detect cancer much cheaper and faster.
The Australian scientists from the University of New South Wales (UNSW) who developed the method, said they are now able to detect very low levels of microRNAs, linked with cancerous tumors and metastasis, in blood samples of significantly lower volumes.
“What this means is the technology has the potential to determine the levels of microRNA just from a finger prick test,” Prof. Justin Gooding from UNSW said.
The low levels of sample needed, as well as the efficiency of the process in detecting microRNAs, makes the method much easier than was previously required, as well as more financially feasible.
“It could be orders of magnitude cheaper,” Gooding said.
“Our method takes 30 minutes compared with almost 12 hours for quantitative polymerase chain reaction.”
What make the new method so effective is the use of magnets to attract the microRNAs.
Scientists create gold-coated magnetic nano-particles which latch onto a high portion of the present microRNAs, and then capture the nano-particles and newly attached microRNAs with a magnet.
“Because the capture is so effective, we get higher sensitivities and can detect much lower limits,” Gooding said.
“And since we bring them back to the electrode under a magnet, our response time is much faster.”
Gooding said he would expect the technology to be available within three years, pending regulatory approvals.